生命科学 / 医学

化学分子构效关系（SAR）图

靶点分子结构 + 修饰位点 + 活性数据矩阵的构效关系研究图。

完整 Prompt

Create a cell-signaling mechanism pathway diagram.

Layout:
- Show extracellular ligand binding to a membrane receptor at the cell membrane.
- Downstream cascade: receptor activation -> adaptor protein -> kinase 1 -> kinase 2 -> transcription factor -> nucleus -> target gene expression.
- Include one inhibitory regulator and one feedback loop.
- Color-code molecule classes: receptors, kinases, transcription factors, inhibitors, and genes.
- Use arrowheads for activation and T-bars for inhibition.

Style:
- Life-science pathway figure on white background.
- Clean vector-like molecular icons, readable labels, and consistent spacing.
- Use navy text, teal activation arrows, coral inhibition marks, and subtle cell-boundary shading.
- Suitable for molecular biology papers, pathway summaries, and grant figures.

立即试用此 Prompt

适用场景

适合药物化学、活性筛选、靶点研究等论文的构效关系配图。

变体

Drug-target overlay

Same pathway, but overlay drug-target stars on the molecules being targeted by a candidate compound (e.g. a star on HDAC and a star on mTOR), with a small drug-name label next to each star.

使用建议

分子骨架二维线画 + 修饰位点彩色高亮是 SAR 图的经典形式。
活性数据矩阵 + 颜色映射比纯数字表格更直观。
中文药学术语必须规范，例如"羟基修饰"而非"OH 修饰"。

常见问题

How do I draw a phosphorylation event?

Add "Show phosphorylation as a small orange P circle attached to the substrate, connected to the kinase by an arrow."